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It's unknown if it contains any supernatural properties. Presumably, as with demons, the presence of an angel may change the blood somewhat as Castiel is unable to use his own blood in a ritual that requires human blood, and his blood as a fallen angel proves to be part of the Bone Of Righteous Mortal Washed In the Three Bloods of Fallen, the weapon that can kill a Leviathan.
- Season 4
- Season 5