Joanie Pike is the wife of Larry Pike, a land developer who builds a house estate in Oasis Plains, Oklahoma.
Joanie's husband Larry unknowingly builds houses on land that carries a curse. This curse causes bugs to attack people. Sam and Dean Winchester come to investigate the town after at least one death occurs.
Shortly after, Joanie and her family become targets, leading the brothers and Joanie's son Matt to work desperately to save them. All of them manage to survive in the end.