Milwaukee is a city in the U.S. state of Wisconsin.
Sam and Dean investigate a series of crimes and suicides in Milwaukee, Wisconsin, wherein people are behaving out of character in stealing from their place of business and then committing suicide shortly thereafter. During their investigation, they come across Ronald "Ron" Reznick, a victim who has conspiracy theories about "Mandroids". His amateur research reveals to Sam and Dean that the perpetrator of these crimes is in fact a Shapeshifter. ("Nightshifter")