Niveus Pharmaceuticals employed several researchers. The company held its own tests with animals such as monkeys. Its website indicated the company had branches worldwide and was part of a larger group called Niveus International. Niveus Pharmaceuticals had its own warehouse storages and its own crew for product deliveries.
Upon the rise of the horseman Pestilence, a swine flu epidemic was raised. In response to this, the public demand for vaccines greatly increased. Vaccines were manufactured and were planned to be distributed. However, a demon in the guise of a janitor infiltrated the pharmaceutical company and inoculated the Croatoan virus on the workers. Eventually, the entire company was taken over and the vaccines were contaminated with the virus.