Supernatural changes its opening credits each season, unlike many other series. Some episodes in each season will have unique, thematic title cards.
The first season's title card was fairly simple, the word "Supernatural" zoomed in and then out of the screen. It mimics the jerky movements of Supernatural's ghost's flickering. An alternative, but not used title sequence was produced and published on the Season 1 DVD as a special feature.
This title card features the word "Supernatural" appearing out of bursting flames with the letter "A" in the form of a pentagram, a key component of a Devil's Trap. The fire may allude to Hell, due to increased demonic activity in this season, or the manner of Mary Winchester's and Jessica Moore 's deaths.
A pair of skeletal of ghostly hands appear followed by the Key of Solomon symbol appears followed by "Supernatural" amidst what look like thunderclouds, or more likely, a demonic storm that reflected the opening of the Devil's Gate in the season 2 finale, or the demon horde Lilith sent in Jus in Bello.
A Very Supernatural ChristmasEdit
This episode's title card is preceded by a version of the old CBS Special Presentation Indent. Sleigh bells are heard and a Christmas ornament explodes on the screen to reveal the episode's title.
A bunch of presumably angel wings flap followed by the Title. A sound of a high-pitched scream is later added in the second episode. The usual animalistic growl is then heard before the title card fades to black.
This episode's title card was designed to fit the look of the old school black and white films from the early to mid-1900s.
The Monster At The End Of This BookEdit
As the other seasons, "Supernatural" appears on the screen, but this time with a drop of blood dispersing in the background, accompanied by the sound of a heart beat, angels whispering, and a high pitch sound. All these most likely allude to demon blood, which was Sam's link to his powers, or the bloodline which links the Winchester brothers to their respective archangels, or even the use of blood on the Angel Banishing Sigil.
In Changing Channels the Supernatural Sitcom Theme Song plays over opening credits which mimic those of 80s sitcom like Full House. The opening sequence is light, humorous and in full contrast to the usual title cards the series uses.
A pane of glass shatters, revealing the title "Supernatural". It likely references Sam's shattered mind, or the Wall, ultimately broken, to protect him.
Clap Your Hands If You BelieveEdit
In Clap Your Hands If You Believe, the opening credits to the episode are an homage to the 1990s series The X-Files, using similar music and images. The final text “The Truth is in There” is a twist on the X-Files catchphrase “The Truth Is Out There”. The sequence bears a few similarities to the unused title sequences found as an Easter egg on the season one DVDs.
The opening titles this episode are a homage to the 1960s Western series Bonanza. The music played during the credits is somewhat similar to Ennio Morricone's "The Ecstasy of Gold," a piece he wrote for the Clint Eastwood movie "The Good, the Bad and the Ugly."
Black text on a white background. The word "Supernatural" appears out of thick black explosion of mist and is dripping black fluid like ectoplasm or ink, probably Leviathan blood.
Season 7, Time For a WeddingEdit
A wedding cake explodes, morphing into the goo of the Season 7 titles. The Bride and Groom figurine falls in front of the screen before the Supernatural logo flies towards the screen.
Plucky Pennywhistle's Magical MenagerieEdit
Gold text on a background of glyphs similar to the ones on The Word of God. The "E" and the two "A"'s in the title "Supernatural" briefly turn into glyphs themselves several times. Whispering can be heard.
The title "Supernatural" appears over a set of burning angel wings, that explodes in a blinding white light.
A homage to The Wizard of Oz. The message on the lower left reads "This is for the SPNFamily whose dedication and love drive us to continue creating this wonderful world. Keeping up the Family Business". However this title card did not appear on the show.
The usual burning angel wings of the season sprout out before being retracted and replaced by a bright white light, and blue in-tact angel wings. The Supernatural name is replaced by the name Metatron.
Angelic blue light bursts out, following it demonic black smoke. As it spreads, a pentagram can be seen. This likely alludes to the season's primary antagonist, Rowena and her witchcraft and her combative relationship with Crowley.